game only works in safe mode

I've got this game that only loads in safe mode,when i try normal mode this error comes up "Jack the ripper .exe has stopped working windows is checking for a solution to the problem" then a second error "Jack the ripper .exe has stopped working a problem caused the program to stop working correctly.Windows will close the program and notify you if a solution is available".Have you any idea what the problem is and how i can fix it please,
Paul